Thyrotropin-releasing hormone receptors -- similarities and differences
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G PROTEIN-COUPLED RECEPTOR SIGNALLING IN NEUROENDOCRINE SYSTEMS Thyrotropin-releasing hormone receptors – similarities and differences
Thyrotropin-releasing hormone (TRH) initiates its effects by interacting with cell-surface membrane receptors. Two G protein-coupled receptors for TRH, TRH receptor type 1 (TRH-R1) and TRH receptor type 2 (TRH-R2), have been cloned from mammals. In this review, we compare TRH-R1 and TRH-R2 with regard to their tissue distribution, binding affinities for TRH and TRH analogs, basal and activated ...
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ژورنال
عنوان ژورنال: Journal of Molecular Endocrinology
سال: 2003
ISSN: 0952-5041,1479-6813
DOI: 10.1677/jme.0.0300087